Thirty-eight McGill research projects have received federal grants through the CFI’s John R. Evans Leaders Fund, which will provide them with state-of-the art research infrastructure needed to foster innovation.

By Amanda Testani, Office of VP Research & Innovation

The Government of Canada through the Canada Foundation for Innovation (CFI) recently announced their funding investment of more than $96 million to support 377 new research infrastructure projects at 55 institutions from coast to coast. The CFI also announced the funding of projects through the John R. Evans Leaders Fund (JELF) in partnership with the Canada Research Chairs (CRC) Program, investing $4.6 million in 21 Chairs at 16 institutions to provide them with the innovative tools they need to pursue their valuable work.

Thirty-eight McGill research projects have received a combined total of $9.3M in federal grants through this round of JELF. The fund helps universities attract top talent in diverse fields of research by providing them with the highly specialized research infrastructure they need to be leaders in their field. The recipients will also receive matching funds from the Quebec government for their research endeavours.

Professors Jörg Hermann Fritz and Corinne Maurice of the Department of Microbiology and Immunology, and Bastien Castagner of the Department of Pharmacology and Therapeutics, received $352,778 in JELF funding for their project on harnessing microbiota metabolism for human health benefits. The project will focus on the ill-defined relationship between bacteria in the human gut, metabolism and the immune system. The research will help design new, more effective drugs to treat inflammatory bowel diseases, obesity, asthma and other chronic diseases.

One McGill project received $520,000 in JELF funding, in partnership with the Canada Research Chairs (CRC) program. Professor Stephen Lomber of the Department of Physiology and Canada Research Chair in Brain Plasticity and Development, received $520,000 from the JELF and CRC partnership to establish an internationally recognized laboratory with state-of-the-art facilities for the study of brain plasticity and auditory neuroscience. The laboratory will help researchers understand how the brain processes sound, and how to best design therapeutic strategies for the 300,000 Canadians burdened with profound hearing loss.

McGill Faculty of Medicine & Health Sciences CRC-JELF recipients:
Hearing Loss and Restoration Laboratory

Professor Stephen Lomber of the Department of Physiology, Faculty of Medicine and Health Sciences, is the principal investigator.

$520,000 from the CRC-JELF partnership; $520,000 matching provincial funds.

List of McGill JELF recipients:

Creation of a Multidisciplinary Sleep Laboratory at the Neuro

Professors Julien Doyon and Birgit Frauscher of the Department of Neurology and Neurosurgery, Faculty of Medicine and Health Sciences, are the principal investigators.

$254, 296 from JELF; $254, 296 matching provincial funds.

Harnessing Microbiota Metabolism for Human Health Benefits

Professors Jörg Hermann Fritz and Corinne Maurice of the Department of Microbiology and Immunology, and Bastien Castagner of the Department of Pharmacology and Therapeutics, Faculty of Medicine and Health Sciences, are the principal investigators.

$352,778 from JELF; $352,778 matching provincial funds.

MAP-PRO: An Electronic Database and Learning Hub for Canadian Early Psychosis Services

Professors Srividya Iyer and Manuela Ferrari of the Department of Psychiatry, Faculty of Medicine and Health Sciences, are the principal investigators.

$80,000 from JELF; $80,000 matching provincial funds.

Conformational Dynamics of Complex Proteins in Health and Diseases

Professor Gergely Lukacs of the Department of Physiology, Professor Kalle Gehring of the Department of Biochemistry, and Jean-Francois Trempe of the Department of Pharmacology and Therapeutics, Faculty of Medicine and Health Sciences, are the principal investigators.

$592,636 from JELF; $592,636 matching provincial funds.

Blood-based Biomarkers for Ageing-related Brain Diseases

Professors Pedro Rosa-Neto of the Department of Psychiatry, Gerhard Multhaup of the Department of Pharmacology and Therapeutics, and Angela Genge of the Department of Neurology and Neurosurgery, are the principal investigators.

$417,175 from JELF; $417,175 matching provincial funds.

Metabolism of Stress-regulated Genes in Health and Disease using Single Molecule Imaging

Professor Maria Vera Ugalde of the Department of Biochemistry, Faculty of Medicine and Health Sciences, is the principal investigator.

$200,000 from JELF; $200,000 matching provincial funds.

Drivers of Breast Cancer Progression Identified within Arm-level Somatic Copy Number Alterations

Professor Logan Walsh of the Department of Human Genetics, Faculty of Medicine and Health Sciences, is the principal investigator.

$109,179 from JELF; $109,179 matching provincial funds.

The Role of Lipoma Preferred Partner (LPP) in Regulating Breast Cancer Progression

Professors Claire Brown of the Department of Physiology and Peter Siegel of the Departments of Medicine, Biochemistry, and Anatomy and Cell Biology, Faculty of Medicine and Health Sciences, are the principal investigators.

$744,304 from JELF; $744,304 matching provincial funds.

Muscle Stem Cell Biology in Health and Disease

Professor Natasha Chang of the Department of Biochemistry, Faculty of Medicine and Health Sciences, is the principal investigator.

$149,582 from JELF; $149,582 matching provincial funds.

Mechanism and Therapy for Autism Spectrum Disorders Associated with Copy Number Variants

Professor Wei-Hsiang Huang of the Department of Neurology and Neurosurgery, Faculty of Medicine and Health Sciences, is the principal investigator.

$169,634 from JELF; $169,634 matching provincial funds.

Development of Strategies to Better Understand and Control the Long-term Side Effects of Radiotherapy

Professor John Kildea of the Department of Oncology, Faculty of Medicine and Health Sciences, is the principal investigator.

$87,579 from JELF; $87,579 matching provincial funds.

Mapping Dopamine Circuits in the Healthy and Diseased Brain

Professor Jean-Francois Poulin of the Department of Neurology and Neurosurgery, Faculty of Medicine and Health Sciences, is the principal investigator.

$294,592 from JELF; $294,592 matching provincial funds.

Circulating Immune Cells and Interactions in the Nervous System

Professor Jo Anne Stratton of the Department of Neurology and Neurosurgery, Faculty of Medicine and Health Sciences, is the principal investigator.

$141,863 from JELF; $141,863 matching provincial funds.

Read CFI’s official press release.

August 19 2020