Photo: Nicolas Morin
Photo: Nicolas Morin

The Cole Foundation continues its support of promising young scientists conducting research on leukemia and lymphomas in children and young adults with the announcement of fourteen new fellowship grants and one new investigator grant for a total funding value of $700,000.

Since the inception of these grants eight years ago, the Cole Foundation has contributed over $6 million to more than 115 researchers in laboratories and hospitals situated in the Greater Montreal area through collaborations with l’Université de Montréal; McGill University; and INRS – Institut Armand-Frappier Research Centre.

“The Cole Foundation is committed to helping to develop the next generation of researchers, said Barry Cole, President of the foundation. The medical faculties at the Université de Montréal and McGill University, as well as the Institut national de recherché scientifique (INRS) – Institut Armand-Frappier are working diligently to advance the fight against pediatric cancer and we’re pleased to be able to contribute to these efforts by providing grants to deserving young researchers.”

“The continued support of the Cole Foundation to McGill and Quebec’s other leading institutions enables our early-career scientists to be at the forefront of pediatric leukemia research,” said Dr. David Eidelman, Vice-Principal (Health Affairs) and Dean of Medicine at McGill University. “This is a wonderful example of how philanthropic collaboration fosters discovery for the benefit of the communities we serve.”

“It is an immense pleasure for me to be able to once again thank the Cole Foundation on behalf of the ten grant recipients researching pediatric leukemia from the l’Université de Montréal, declared Dr.  Hélène Boisjoly, Dean of the Faculty of Medicine at l’Université de Montréal. The announcement of the financial contribution from the Cole Foundation has been a highly anticipated day for researchers over the past eight years. It provides them with very good news.”

In connection with the new round of grants, the Cole Foundation also organized a day of discussions on the state of research in the field of pediatric cancer, held May 9 at McGill University. The day-long event included a special presentation by Dr. Charles Mullighan of St. Jude Children’s Research Hospital in Memphis, Tennessee, who spoke about the acute lymphoblastic leukemia genome, providing insights from pathogenesis to therapy. 

About the Cole Foundation

The Cole Foundation offers two-year fellowships to clinical, doctoral and postdoctoral graduate scientists dedicated to research in leukemia and leukemia-related diseases in children and young adults. Through its fellowships, the Cole Foundation has committed more than $6 million to support leukemia researchers in Greater Montreal laboratories and hospitals. The Cole Foundation was created in 1980 by the late businessman John N. (Jack) Cole to support Montreal-based research in pediatric oncology and hematology. He established the Penny Cole Laboratory at the Montreal Children’s Hospital and the Jack Cole Chair in Pediatric Oncology and Hematology at McGill University.

Cole Foundation Research Fellowships (2014–2016)
McGill University
Qianyu Guo, Lady Davis Institute, Experimental Medicine
Project: Elucidate the mechanisms of the increased anti-leukemic potency of darinaparsin compared to arsenic trioxide
Rayelle Itoua Maiga, McGill University, Biochemistry
Project: Engineering Chromosome Translocations to Recapitulate Primary Events of CML
Said Izreig, McGill University, Physiology
Project: Repression of LKB1 by miR-17/20 contributes to Myc-driven metabolism in lymphoma
Peng Wang, Rosalind and Morris Goodman Cancer Research Centre
Project: Deciphering the Role of PP2A-855 Localization in Translation Control in Leukemia
Université de Montréal
Haithem Barbour, Maisonneuve-Rosemont Hospital
Project: Deregulations of DNA methyoation in pediatric hematological malignancies
Nadine Sen Nkwe Dibondo, Maisonneuve-Rosemont Hospital
Project: Déregulation de l’ubiquitination de l’histone H2A dans les leucémies des enfantset des jeunesadultes
Nicolas Garnier, CHU Centre de recherche Sainte-Justine
Project: Targeted therapy strategy for childhood ALL
David Kachaner, IRIC, Biology
Project: Inhibition of Polo-like kinase 1 interactions to disrupt mitosis in leukemia cells
 Vincent-Philippe Lavallée, Maisonneuve-Rosemont Hospital
Project: Development of a novel molecular classification for improved risk stratification of AML patients based on next-generation sequencing
Valérie Lemay, Université de Montréal, Kinesiology
Project: Modifications à long terme des paramètrescardiorespiratoires chez des survivants de leucémielymphoblastiqueaiguë: lien avec la pratiqued’activité physique
Alena Motorina, Maisonneuve-Rosemont Hospital
Project: Understanding oncogene cooperation in pediatric acute megakaryoblastic leukemia
Alexandre Rouerre, IRIC, Medicine
Project: Le rôle de l’immunoprotéasomedansl’oncogenèse
Jérôme Roger, IRIC, Pathology and Cellular Biology
Project : Investigating the role of RSK in acute myeloid leukemia growth and chemoresistance
Clarisse Thiollier, IRIC, Medicine
Project: Inactivation de p53 dans les leucémiesaigüesmyéloïdes
Cole Foundation New Investigator Program
Valérie Marcil, Sainte-Justine Hospital Research Center 
Project: Cardiometabolic long-term effects in ALL survivors

McGill Faculty of Medicine: http://www.mcgill.ca/medicine/

Faculté de médecine de l’Université de Montréal: www.med.umontreal.ca

INRSInstitut Armand-Frappier: www.iaf.inrs.ca

Cole Foundation: www.colefoundation.ca

May 16, 2014