The Lady Davis Institute and the

McGill University-Génome Québec Innovation Centre


A McGill Distinguished Lecture in Human Genetics: 

GWAS, DNA Sequencing, and immunogenomics in cancer research


Yusuke Nakamura MD, PhD

University of Chicago, Department of Medicine and Surgery, Center for Personalized Therapeutics

Tuesday, June 11, 2013, from 3:30-5:00pm

Charles Martin Amphitheatre, McIntyre Medical Sciences Building

3655 Promenade Sir William Osler, Montreal, Quebec

Faculty of Medicine

Department of Human Genetics

“Genetic variations and mutations have been utilized as useful tools for (1) identifying the genes responsible for hereditary cancer syndromes, (2) identifying genes susceptible to various common diseases including cancer, and (3) establishing the prediction system for the efficacy or risk of adverse reactions of various drugs. In addition to the examination of genetic variation, more attention should be paid to identifying variations in immune cells. Recent studies have indicated that the immune response in cancer patients significantly influences the clinical response of chemotherapy or radiation therapy. Characterization of immune responses after organ transplantation should also contribute to a better understanding of the molecular mechanism of organ transplantation rejection. Therefore, characterization of differences in immune cells, such as the T-cell repertoire, is essential for future cancer treatment. In my talk, I will summarize the importance of different types of genetic variation in the cancer research field.”

May 29, 2013