Infertility affects about one in seven couples worldwide, yet for many, the biological cause remains a mystery. In a new study published in Reproductive BioMedicine Online, researchers at The Research Institute of the McGill University Health Centre (The Institute) and international collaborators used advanced genetic sequencing to uncover new mutations that can cause infertility in both men and women. Their findings offer new guidance for how to bring genomic diagnosis into clinical practice.
“Understanding the underlying causes of infertility can transform patient care,” said Rima Slim, PhD, Senior Scientist in the Child Health and Human Development Program at The Research Institute of the McGill University Health Centre (The Institute) and senior author of the study. “A precise genetic diagnosis not only helps clinicians tailor treatment options, but also provides patients with clarity and reassurance after years of uncertainty.”